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Anat Cell Biol

Published online November 17, 2022

https://doi.org/10.5115/acb.22.118

Copyright © Korean Association of ANATOMISTS.

The clinical anatomy of the accessory submandibular gland: a comprehensive review

Andrea Yazbeck1 , Joe Iwanaga2,3,4,5,6 , Jerzy A. Walocha7 , Łukasz Olewnik8 , R. Shane Tubbs1,4,5,9,10,11,12

1Department of Structural & Cellular Biology, Tulane University School of Medicine, New Orleans, LA, USA, 2Division of Gross and Clinical Anatomy, Department of Anatomy, Kurume University School of Medicine, Kurume, Fukuoka, 3Dental and Oral Medical Center, Kurume University School of Medicine, Kurume, Fukuoka, Japan, 4Department of Neurosurgery, Tulane Center for Clinical Neurosciences, Tulane University School of Medicine, New Orleans, LA, 5Department of Neurology, Tulane Center for Clinical Neurosciences, Tulane University School of Medicine, New Orleans, LA, USA, 6Department of Oral and Maxillofacial Anatomy, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan, 7Department of Anatomy, Jagiellonian University Medical College, Krakow, 8Department of Anatomical Dissection and Donation, Medical University of Lodz, Lodz, Poland, 9Department of Anatomical Sciences, St. George’s University, St. George’s, Grenada, West Indies, 10Department of Neurosurgery and Ochsner Neuroscience Institute, Ochsner Health System, New Orleans, LA, 11Department of Surgery, Tulane University School of Medicine, New Orleans, LA, USA, 12University of Queensland, Brisbane, Australia

Correspondence to:Joe Iwanaga
Department of Neurosurgery, Tulane Center for Clinical Neurosciences, Tulane University School of Medicine, New Orleans, LA 70112, USA
E-mail: iwanagajoeca@gmail.com

Received: June 15, 2022; Revised: October 19, 2022; Accepted: October 20, 2022

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

An accessory submandibular gland is a rare variation. As such, there is limited literature regarding the embryology, anatomy, variations, clinical imaging, and pathology of the accessory submandibular gland. In this article, we review the existing literature on the accessory submandibular gland from clinical and anatomical perspectives. The goal of this review is to provide comprehensive knowledge of this variation which can be useful for oral and maxillofacial/head and neck surgeons, radiologists, and anatomists. Within this review, the embryologic origin as well as the anatomy of the accessory submandibular gland is detailed. Several imaging modalities which can be used to visualize the accessory submandibular gland are outlined as well as its variations. Lastly, this review investigates several reported clinical considerations regarding the accessory submandibular gland including sialoliths, Wharton’s duct obstruction, and pleomorphic adenoma.

Keywords: Submandibular gland, Salivary gland, Gross anatomy, Clinical anatomy

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