Fig. 7. Photomicrographs of the CA1 region of the hippocampal sections of rats Cresyl violet, ×400. (A) Control showing normal Nissl substance around the cytoplasm of the neurons, (B) I/R micrograph indicates degenerated pyramidal cells without Nissl substances, (C–E) Cr, Cy, and DN, I/R+50 mg/kg MNC, I/R+100/200 mg/kg PTT close to normal neuronal cells with Nissl substances in the CA1. (F) is a graph of staining intensity across the group. n=5; mean±SEM, one-way ANOVA, Tukey’s post-hoc test. CA1, cornu ammonis 1; Pk, pyknosis; Dn, degenerating pyramidal neurons; Cy, cytoplasmic vacuolation; Cr, chromatolysis; Control, 2 ml/kg of distilled water+a drop of dimethyl sulphoxide; I/R, ischemia/reperfusion; MNC, minocycline; PTT, phenolics fraction of Tetrapleura tetraptera. *P<0.05; 50 mg/kg MNC compared to I/R group, **P<0.01; 200 mg/kg PTT compared to I/R group, ***P<0.001; I/R compared to control.
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