The growth factor, endpoint, and source, melatonin as a supplement, in the three-dimensional culture system in spermatogonial stem cells
Source | Cells | GF | Feeders/substrate | Endpoint | Reference (yr) |
---|---|---|---|---|---|
Mice | SSCs | FBS, GDNF, LIF | 3D SACS | Melatonin as an antioxidant increases viability of SSCs by reducing oxygen free radicals and improves culture of SSCs. | Navid et al. (2017) [13] |
GF, growth factor; SSC, spermatogonial stem cell; 3D SACS, three-dimensional soft agar culture system.
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