Fig. 10. Nisin blocked globose shape type 3D cell cluster formation. At 0 to 24 hours or 3 to 24 hours nisin treated cell clusters showed a sea urchin-shape, compared to that in the 6 to 24 hours treated cell cluster and control. HaCaT cells in minimal cell attachment plates were treated with nisin or the vehicle for indicated periods from seeding. Images of phase-contrast microscopy. Scale bar represent 500 μm.
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