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pISSN 2093-3665 eISSN 2093-3673
Fig. 2.
Fig. 2. Representative semi-thin blue-stained sections of the rat medulla oblongata of control and melatonin aged 7 days: showing normal neurons with vesicular nuclei and prominent nucleoli (black arrow), different neuroglia (A, O, and M) and myelinated axons (crossed arrows). CYP treated group of the same age showing some shrunken neuronal bodies with an irregular outline, hardly identified nuclei, and deeply stained vacuolated cytoplasm (dashed arrow). Some neurons appear to have deeply stained nuclei and cytoplasm (curved arrow)., Numerous fine vacuoles were detected in neurons, numerous A, and neuropil devoid of myelinated axons (star). CYP/melatonin treated group shows nearly normal neurons with prominent nucleoli (black arrow), neurons containing coarse clumps of heterochromatin (white arrow), myelinated axons (crossed arrow). Darkly stained neurons (curved arrow) and dilated blood vessels are still observed. Sections of the control and melatonin groups aged 21 days showing large multipolar neurons with large nucleus & prominent nucleolus (black arrow). The neuron is surrounded by dense neuropil containing more myelinated axons (crossed arrow). CYP treated group of the same age shows neurons with numerous fine vacuoles (curved arrows), a large number of A, and neuropil devoid of myelinated axons (star). CYP/melatonin treated group shows neurons with pale vesicular nuclei with prominent nucleoli (black arrows) and myelinated axons in the surrounding neuropil. However, few darkly stained vacuolated neurons are detected. A, astrocyte; CYP, cypermethrin; M, microglia; O, oligodendrocyte; PND, postnatal day. Scale bar=10 μm.
Anat Cell Biol 2020;53:460~470 https://doi.org/10.5115/acb.20.193
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