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pISSN 2093-3665 eISSN 2093-3673
Fig. 1.
Fig. 1. Representative H&E staining of rat medulla oblongata of control and melatonin aged 7 days: showing medulla neurons appeared small in size, varied in shape and had round nuclei (black arrows). The neuropil contains different neuroglia (O, A, and M) and blood vessels (arrowheads). Medulla oblongata of CYP treated group of the same age shows neurons with central chromatolysis (curved arrows), degenerated neurons and pyknotic nuclei (dashed arrows), dilated blood vessels (black arrowheads) and numerous A. CYP/melatonin treated group resulted in almost normal appearing neuronal cells, except for chromatolysis (curved arrow) and degenerated neurons and pyknotic nuclei (dashed arrow) in some neurons. Increased number of O and deceased of A. Control and melatonin groups aged 21 days, the neurons appear larger (black arrow). Many oligodendrocytes (arrows with rounded end) are observed in the neuropil. CYP treated group show chromatolysis of almost all neurons (curved arrows), a large number of A and v. Co-administration of CYP/melatonin shows more or less normal neurons (black arrow). However, some degenerated cells (curved arrow) with loss of nuclear details could be detected. Few A and more O could be observed. A, astrocyte; CYP, cypermethrin; M, microglia; O, oligodendrocyte; PND, postnatal day; v, vacuolated neuropil. Scale bar=20 μm.
Anat Cell Biol 2020;53:460~470 https://doi.org/10.5115/acb.20.193
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